Manufacturers are currently marketing nicotine pouches and e-cigarettes with synthetic nicotine in the US. Whether derived from tobacco plants or synthetically developed in a laboratory, nicotine is an addictive drug with known adverse consequences for fetal development and adolescent brain development.
Given public health considerations, synthetic nicotine products warrant urgent attention from policy makers, clinicians, and researchers. Sufficient scientific evidence about nicotine’s harmful effects exists to caution young people and pregnant adults against use of synthetic nicotine and to justify inclusion of synthetic nicotine products in existing regulatory efforts.
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